> ## Documentation Index > Fetch the complete documentation index at: https://docs.pav.bio/llms.txt > Use this file to discover all available pages before exploring further. # Programs > Drug development programs from company-published pipelines: drug, indication, phase, modality, target, mechanism and linked trials. ## Overview A program is one drug in one indication at one company, as the company publishes it in its pipeline. Each program carries a normalized phase, a modality, the molecular target and mechanism when disclosed, the clinical trials linked to it, and the page it was read from. Questions this dataset answers: * Which companies have an oral GLP-1 agonist in development for obesity? * Which KRAS G12C inhibitors are in Phase 3, and in which indications? * What else is being developed that looks like this program? * What is Eli Lilly's full Phase 3 pipeline? ## Coverage | Programs | Companies | Normalized phases | Normalized modalities | | -------- | --------- | ----------------- | --------------------- | | 27,000+ | 6,500+ | 9 | 19 | Counts are from September 2026. Get current counts, and program counts per phase and modality, from [`GET /v1/stats`](/api-reference/stats/dataset-summary-statistics). Partial fields are listed in [Coverage and sources](/concepts/coverage-and-sources). ## Key fields | Field | Description | | -------------------------------------- | ------------------------------------------------------------------------------------------------------------------------------------------------------------- | | `id` | Pav program id. Stable across updates; a phase change updates the program, it does not create a new one. | | `company_id`, `company`, `short_name` | Owning company: Pav id, display name, slug. | | `drug` | Drug or asset name as the company publishes it. | | `indication` | Indication as the company publishes it. | | `phase` / `phase_norm` | Phase as published, and the normalized phase (`Preclinical`, `Phase 1`, `Phase 1/2`, `Phase 2`, `Phase 2/3`, `Phase 3`, `Filed`, `Registration`, `Approved`). | | `modality` / `modality_norm` | Modality as published, and the normalized modality (`small_molecule`, `antibody`, `adc`, `cell_therapy`, ...). | | `target`, `mechanism_of_action` | Molecular target and mechanism, when disclosed. | | `partners` | Partner companies named with the program. | | `clinical_trials[]` | Linked ClinicalTrials.gov studies (`nct_id`, phase, status, sponsor). | | `indication_terms[]`, `target_terms[]` | Indication mapped to MONDO terms and target mapped to NCIT terms, when available. | | `source_url`, `source_checked_at` | The company page the program was read from, and when Pav last read it. | Full schema: [List and search pipeline programs](/api-reference/programs/list-and-search-pipeline-programs). ## Endpoints | Endpoint | Use | | ------------------------------------------------ | ------------------------------------------------ | | `GET /v1/programs` | Search (`q`) or filter programs. | | `GET /v1/programs/{program_id}` | One program with its trials and ontology terms. | | `GET /v1/programs/{program_id}/similar-programs` | Programs most similar to a given program. | | `GET /v1/programs/autocomplete` | Search-as-you-type suggestions for a search box. | | `GET /v1/companies/{company_id}/programs` | One company's programs. | ## Filters All filters are optional, repeatable, and combine with AND. Repeating a filter matches any of its values. | Parameter | Matches | Example | | -------------------------- | ------------------------------------------------------------------------------------------------------------------ | --------------------------- | | `q` | Relevance-ranked search that matches meaning as well as exact words. | `oral GLP-1 obesity` | | `phase` | Normalized phase label, exactly as in `phase_norm`. | `Phase 3` | | `modality` | Modality token (as in `modality_norm`) or its display label. Unknown values return `422`. | `adc`, `Small molecule` | | `target` | Target, case-insensitive exact match. | `KRAS` | | `indication` | Indication, case-insensitive exact match. | `Obesity` | | `drug` | Drug name, case-insensitive exact match. | `Tirzepatide` | | `company` | Company display name. | `Eli Lilly` | | `short_name`, `company_id` | Company slug or Pav id. | `eli_lilly`, `218` | | `sort`, `direction` | Listing order (not with `q`): `company`, `drug`, `indication`, `target`, `phase`, `modality`, `source_checked_at`. | `sort=phase&direction=desc` | | `include_total` | Exact match count on filter-only listings. | `true` | | `limit`, `offset` | Page size (1–5000, default 50) and offset. | `limit=100` | `phase` takes the label shown in `phase_norm` (`Phase 3`), not a token such as `phase_3`. A value that matches nothing returns an empty `data` array, not an error. ## Search programs by mechanism and phase `q` finds programs by meaning, not only by exact words. Add filters to narrow the ranked results. ```bash cURL theme={null} curl -G https://api.pav.bio/v1/programs \ -H "Authorization: Bearer $PAV_API_KEY" \ --data-urlencode "q=KRAS G12C inhibitor" \ --data-urlencode "phase=Phase 3" \ --data-urlencode "limit=3" ``` ```python Python theme={null} import os import requests resp = requests.get( "https://api.pav.bio/v1/programs", headers={"Authorization": f"Bearer {os.environ['PAV_API_KEY']}"}, params={"q": "KRAS G12C inhibitor", "phase": "Phase 3", "limit": 3}, ) resp.raise_for_status() for p in resp.json()["data"]: print(p["company"], "|", p["drug"], "|", p.get("indication", ""), "|", p.get("target")) ``` ```javascript JavaScript theme={null} const params = new URLSearchParams({ q: "KRAS G12C inhibitor", phase: "Phase 3", limit: "3" }); const resp = await fetch(`https://api.pav.bio/v1/programs?${params}`, { headers: { Authorization: `Bearer ${process.env.PAV_API_KEY}` }, }); const { data } = await resp.json(); for (const p of data) console.log(p.company, "|", p.drug, "|", p.indication, "|", p.target); ``` ```json Example response (trimmed) theme={null} { "data": [ { "id": 3407, "company_id": 313, "company": "Merck", "drug": "calderasib", "indication": "Colorectal cancer", "phase_norm": "Phase 3", "modality_norm": "small_molecule", "target": "KRAS G12C" }, { "id": 3408, "company_id": 313, "company": "Merck", "drug": "calderasib", "indication": "Non-small cell lung cancer", "phase_norm": "Phase 3", "modality_norm": "small_molecule", "target": "KRAS G12C" } ], "pagination": { "limit": 3, "offset": 0 } } ``` ## Filter and count Without `q`, the endpoint lists programs matching the filters. Pass `include_total=true` for the exact count. Repeat `phase` to match several phases. ```bash cURL theme={null} curl -G https://api.pav.bio/v1/programs \ -H "Authorization: Bearer $PAV_API_KEY" \ --data-urlencode "indication=Obesity" \ --data-urlencode "phase=Phase 2" \ --data-urlencode "phase=Phase 3" \ --data-urlencode "include_total=true" \ --data-urlencode "limit=3" ``` ```python Python theme={null} import os import requests resp = requests.get( "https://api.pav.bio/v1/programs", headers={"Authorization": f"Bearer {os.environ['PAV_API_KEY']}"}, params={ "indication": "Obesity", "phase": ["Phase 2", "Phase 3"], "include_total": "true", "limit": 3, }, ) resp.raise_for_status() body = resp.json() print("total:", body["pagination"]["total"]) for p in body["data"]: print(p["company"], "|", p["drug"], "|", p["phase_norm"]) ``` ```javascript JavaScript theme={null} const params = new URLSearchParams([ ["indication", "Obesity"], ["phase", "Phase 2"], ["phase", "Phase 3"], ["include_total", "true"], ["limit", "3"], ]); const resp = await fetch(`https://api.pav.bio/v1/programs?${params}`, { headers: { Authorization: `Bearer ${process.env.PAV_API_KEY}` }, }); const body = await resp.json(); console.log("total:", body.pagination.total); for (const p of body.data) console.log(p.company, "|", p.drug, "|", p.phase_norm); ``` ```json Example response (trimmed) theme={null} { "data": [ { "id": 24517, "company": "Actelion", "drug": "Canagliflozin", "indication": "Obesity", "phase_norm": "Phase 2" }, { "id": 24695, "company": "Actelion", "drug": "JNJ-64565111", "indication": "Obesity", "phase_norm": "Phase 2" }, { "id": 24387, "company": "Actelion", "drug": "R256918", "indication": "Obesity", "phase_norm": "Phase 2" } ], "pagination": { "limit": 3, "offset": 0, "total": 77 } } ``` `indication` is an exact match on the published indication text. For broader recall across phrasings ("Metabolic (Obesity)", "Obesity / Metabolic Disease"), use `q` instead. ## Find similar programs Given a program id, return the programs most similar to it, ranked by similarity. Useful for finding competitors and analogues. ```bash cURL theme={null} curl https://api.pav.bio/v1/programs/1833/similar-programs \ -H "Authorization: Bearer $PAV_API_KEY" ``` ```python Python theme={null} import os import requests resp = requests.get( "https://api.pav.bio/v1/programs/1833/similar-programs", headers={"Authorization": f"Bearer {os.environ['PAV_API_KEY']}"}, ) resp.raise_for_status() for p in resp.json()["data"]: print(p["company"], "|", p["drug"], "|", p.get("indication", "")) ``` ```javascript JavaScript theme={null} const resp = await fetch("https://api.pav.bio/v1/programs/1833/similar-programs", { headers: { Authorization: `Bearer ${process.env.PAV_API_KEY}` }, }); const { data } = await resp.json(); for (const p of data) console.log(p.company, "|", p.drug, "|", p.indication); ``` ```json Example response (trimmed) theme={null} { "program_id": 1833, "data": [ { "id": 1834, "company": "Eli Lilly", "drug": "Tirzepatide", "indication": "Morbidity and Mortality in Obesity", "phase_norm": "Approved" }, { "id": 1835, "company": "Eli Lilly", "drug": "Tirzepatide", "indication": "Type 1 Diabetes", "phase_norm": "Phase 3" }, { "id": 1832, "company": "Eli Lilly", "drug": "Tirzepatide", "indication": "Higher Doses", "phase_norm": "Phase 2" } ] } ``` ## Get one program `GET /v1/programs/{program_id}` returns the full record, including linked trials and ontology terms. ```json Example response (trimmed): GET /v1/programs/1833 theme={null} { "id": 1833, "company_id": 218, "company": "Eli Lilly", "drug": "Tirzepatide", "indication": "Metabolic Dysfunction-Associated Steatotic Liver Disease", "phase": "Phase 3", "phase_norm": "Phase 3", "modality_norm": "peptide", "mechanism_of_action": "GIP/GLP-1 receptor agonist", "clinical_trials": [ { "nct_id": "NCT07165028", "nct_url": "https://clinicaltrials.gov/study/NCT07165028", "nct_phase": "PHASE3", "nct_sponsor": "Eli Lilly and Company", "nct_status": "RECRUITING" } ], "indication_terms": [ { "ontology": "MONDO", "term_id": "MONDO:0013209", "term_label": "metabolic dysfunction-associated steatotic liver disease" } ], "target_terms": [ { "ontology": "NCIT", "term_id": "NCIT:C191844", "term_label": "Glucagon-Like Peptide 1 Receptor" } ], "source_url": "https://www.lilly.com/science/research-development/pipeline" } ``` ## Related * [Competitive landscape guide](/guides/competitive-landscape) * [Companies](/datasets/companies) and [Clinical trials](/datasets/clinical-trials) * [Search and filters](/concepts/search-and-filters)