curl --request GET \
--url https://api.pav.bio/v1/changes \
--header 'Authorization: Bearer <token>'import requests
url = "https://api.pav.bio/v1/changes"
headers = {"Authorization": "Bearer <token>"}
response = requests.get(url, headers=headers)
print(response.text)const options = {method: 'GET', headers: {Authorization: 'Bearer <token>'}};
fetch('https://api.pav.bio/v1/changes', options)
.then(res => res.json())
.then(res => console.log(res))
.catch(err => console.error(err));<?php
$curl = curl_init();
curl_setopt_array($curl, [
CURLOPT_URL => "https://api.pav.bio/v1/changes",
CURLOPT_RETURNTRANSFER => true,
CURLOPT_ENCODING => "",
CURLOPT_MAXREDIRS => 10,
CURLOPT_TIMEOUT => 30,
CURLOPT_HTTP_VERSION => CURL_HTTP_VERSION_1_1,
CURLOPT_CUSTOMREQUEST => "GET",
CURLOPT_HTTPHEADER => [
"Authorization: Bearer <token>"
],
]);
$response = curl_exec($curl);
$err = curl_error($curl);
curl_close($curl);
if ($err) {
echo "cURL Error #:" . $err;
} else {
echo $response;
}package main
import (
"fmt"
"net/http"
"io"
)
func main() {
url := "https://api.pav.bio/v1/changes"
req, _ := http.NewRequest("GET", url, nil)
req.Header.Add("Authorization", "Bearer <token>")
res, _ := http.DefaultClient.Do(req)
defer res.Body.Close()
body, _ := io.ReadAll(res.Body)
fmt.Println(string(body))
}HttpResponse<String> response = Unirest.get("https://api.pav.bio/v1/changes")
.header("Authorization", "Bearer <token>")
.asString();require 'uri'
require 'net/http'
url = URI("https://api.pav.bio/v1/changes")
http = Net::HTTP.new(url.host, url.port)
http.use_ssl = true
request = Net::HTTP::Get.new(url)
request["Authorization"] = 'Bearer <token>'
response = http.request(request)
puts response.read_body{
"data": [
{
"id": 90211,
"short_name": "pfizer",
"drug": "Danuglipron",
"change_type": "update",
"detected_at": "2026-06-19T04:12:00Z",
"program_id": 9083,
"company_id": 412,
"company": "Pfizer",
"indication": "Type 2 Diabetes",
"territory": "United States",
"prev_phase": "Phase 1",
"new_phase": "Phase 2",
"invalidated_at": "2026-06-20T04:12:00Z",
"invalidation_reason": "source correction"
}
],
"pagination": {
"limit": 100,
"offset": 0,
"total": 590355
},
"next_cursor": "<opaque cursor>"
}{
"error": {
"code": "not_found",
"message": "program 999999 not found",
"request_id": "3f2b9c1d8a7e4f6b9c0d1e2f3a4b5c6d"
}
}{
"error": {
"code": "not_found",
"message": "program 999999 not found",
"request_id": "3f2b9c1d8a7e4f6b9c0d1e2f3a4b5c6d"
}
}{
"error": {
"code": "not_found",
"message": "program 999999 not found",
"request_id": "3f2b9c1d8a7e4f6b9c0d1e2f3a4b5c6d"
}
}{
"error": {
"code": "not_found",
"message": "program 999999 not found",
"request_id": "3f2b9c1d8a7e4f6b9c0d1e2f3a4b5c6d"
}
}List pipeline and clinical-trial change events
Detected changes, newest first, timed by detected_at.
entity=program(default): a program added (insert), a program changing phase or details (update), or a program leaving a company’s pipeline (delete). Each change names itsprogram_id;GET /v1/programs/{program_id}returns that program. Retracted changes are hidden unlessinclude_invalidated=true.entity=trial: ClinicalTrials.gov catalyst changes, one row per trial,kindand registry update date: a new or removed trial (trial), recruitmentstatus,phase,start_date,primary_completion_date,completion_date,results_posted,enrollmentandwhy_stopped, withold_valueandnew_value. Filter withkind,nct_id,change_typeandcompany_id(trials linked to the company through its programs or sponsorship). History starts 2026-06-15.
Page with the returned next_cursor via ?cursor=; it stays gap-free while new changes arrive. since= bounds the start.
curl --request GET \
--url https://api.pav.bio/v1/changes \
--header 'Authorization: Bearer <token>'import requests
url = "https://api.pav.bio/v1/changes"
headers = {"Authorization": "Bearer <token>"}
response = requests.get(url, headers=headers)
print(response.text)const options = {method: 'GET', headers: {Authorization: 'Bearer <token>'}};
fetch('https://api.pav.bio/v1/changes', options)
.then(res => res.json())
.then(res => console.log(res))
.catch(err => console.error(err));<?php
$curl = curl_init();
curl_setopt_array($curl, [
CURLOPT_URL => "https://api.pav.bio/v1/changes",
CURLOPT_RETURNTRANSFER => true,
CURLOPT_ENCODING => "",
CURLOPT_MAXREDIRS => 10,
CURLOPT_TIMEOUT => 30,
CURLOPT_HTTP_VERSION => CURL_HTTP_VERSION_1_1,
CURLOPT_CUSTOMREQUEST => "GET",
CURLOPT_HTTPHEADER => [
"Authorization: Bearer <token>"
],
]);
$response = curl_exec($curl);
$err = curl_error($curl);
curl_close($curl);
if ($err) {
echo "cURL Error #:" . $err;
} else {
echo $response;
}package main
import (
"fmt"
"net/http"
"io"
)
func main() {
url := "https://api.pav.bio/v1/changes"
req, _ := http.NewRequest("GET", url, nil)
req.Header.Add("Authorization", "Bearer <token>")
res, _ := http.DefaultClient.Do(req)
defer res.Body.Close()
body, _ := io.ReadAll(res.Body)
fmt.Println(string(body))
}HttpResponse<String> response = Unirest.get("https://api.pav.bio/v1/changes")
.header("Authorization", "Bearer <token>")
.asString();require 'uri'
require 'net/http'
url = URI("https://api.pav.bio/v1/changes")
http = Net::HTTP.new(url.host, url.port)
http.use_ssl = true
request = Net::HTTP::Get.new(url)
request["Authorization"] = 'Bearer <token>'
response = http.request(request)
puts response.read_body{
"data": [
{
"id": 90211,
"short_name": "pfizer",
"drug": "Danuglipron",
"change_type": "update",
"detected_at": "2026-06-19T04:12:00Z",
"program_id": 9083,
"company_id": 412,
"company": "Pfizer",
"indication": "Type 2 Diabetes",
"territory": "United States",
"prev_phase": "Phase 1",
"new_phase": "Phase 2",
"invalidated_at": "2026-06-20T04:12:00Z",
"invalidation_reason": "source correction"
}
],
"pagination": {
"limit": 100,
"offset": 0,
"total": 590355
},
"next_cursor": "<opaque cursor>"
}{
"error": {
"code": "not_found",
"message": "program 999999 not found",
"request_id": "3f2b9c1d8a7e4f6b9c0d1e2f3a4b5c6d"
}
}{
"error": {
"code": "not_found",
"message": "program 999999 not found",
"request_id": "3f2b9c1d8a7e4f6b9c0d1e2f3a4b5c6d"
}
}{
"error": {
"code": "not_found",
"message": "program 999999 not found",
"request_id": "3f2b9c1d8a7e4f6b9c0d1e2f3a4b5c6d"
}
}{
"error": {
"code": "not_found",
"message": "program 999999 not found",
"request_id": "3f2b9c1d8a7e4f6b9c0d1e2f3a4b5c6d"
}
}Authorizations
Use a personal or organization Pav API key from Pav developer settings. Send it as Authorization: Bearer <api_key>.
Query Parameters
Which feed: program (default) or trial.
program, trial "trial"
Filter to these Pav company ids. Repeatable.
412
Filter by change type: insert, update, delete. Repeatable.
insert, update, delete "update"
entity=trial only: filter by what changed. Repeatable.
trial, status, phase, start_date, primary_completion_date, completion_date, results_posted, enrollment, why_stopped "status"
entity=trial only: filter to these NCT ids. Repeatable.
"NCT05366478"
Only changes detected at or after this timestamp (ISO 8601).
"2026-06-01T00:00:00Z"
entity=program only: include changes later retracted after a correction.
false
Opaque cursor from a prior response's next_cursor. Preferred over offset; wins when both are sent.
Maximum rows to return (1-5000).
1 <= x <= 500050
Zero-based row offset. Prefer cursor, which wins when both are sent.
0 <= x <= 20000000000
Response
Successful Response
- ChangeListResponse
- TrialChangeListResponse
A page of program changes (entity=program) or trial changes (entity=trial).
Page of pipeline change events.
Show child attributes
Show child attributes
Pagination metadata for this page.
Show child attributes
Show child attributes
Opaque cursor to fetch the next page; pass it back as ?cursor=. Null when this page exhausts the feed. Stable under concurrent inserts (unlike offset).
"<opaque cursor>"